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Is Sleep Aids (Ambien, benzodiazepines) toxic to dogs or cats?
Category: Medication | Last reviewed: June 2026
Quick verdict
Dogs
TOXICCats
TOXICSleep Aids (Ambien, benzodiazepines) and dogs
Sleep aids often have a paradoxical effect in pets: instead of sleep they can cause agitation, hyperactivity, vocalising and disorientation, or heavy sedation, depending on the animal. Because of the wide safety margin of these drugs, fatalities are uncommon, but ingestion still needs veterinary monitoring. Combination products that pair a sleep aid with acetaminophen (some night-time cold remedies) are far more dangerous.
Onset
10-60 minutes
Symptoms
- - paradoxical agitation or hyperactivity
- - sedation
- - wobbliness
- - disorientation
- - vocalising
- - panting
- - tremors
- - weakness
What to do now
Contact ASPCA Poison Control (888-426-4435) or your vet. Bring the packaging and check whether it is a combination product containing acetaminophen.
Toxicity is dose-dependent. Your dog's weight and the quantity consumed are both important - include these when you call poison control.
Sleep Aids (Ambien, benzodiazepines) and cats
Cats show the same unpredictable mix of sedation and paradoxical excitement. The greater danger for cats is any combination product containing acetaminophen, which is catastrophically toxic to them.
Onset
10-60 minutes
Symptoms
- - agitation or sedation
- - wobbliness
- - disorientation
- - vocalising
- - tremors
- - weakness
What to do now
Contact ASPCA Poison Control (888-426-4435) or your vet. Confirm the product does not contain acetaminophen.
Data sources
- - ASPCA Animal Poison Control
- - Pet Poison Helpline - Ambien
- - Merck Veterinary Manual
Last reviewed: June 2026
Data error? Email data@treatortoxic.com with a source reference.